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process may also lead to instability of press-fit TKA components in older female patients.63 However, recent data with next-generation press-fit designs have found that cementless TKA is safe in a patient population that was 68% female with a mean age of 80 years old.64 More research

hearing impairment, intellectual disability, and motor disability when compared to other causes of CP. Patients should receive a complete neurological evaluation and perinatal workup. Neuroimaging findings help characterize structural brain abnormalities and predict outcome. References Alarcon A, Martinez-Biarge M, Cabañas F, Hernanz A, Quero J, Garcia-Alix

hearing impairment, intellectual disability, and motor disability when compared to other causes of CP. Patients should receive a complete neurological evaluation and perinatal workup. Neuroimaging findings help characterize structural brain abnormalities and predict outcome. References Alarcon A, Martinez-Biarge M, Cabañas F, Hernanz A, Quero J, Garcia-Alix

hearing impairment, intellectual disability, and motor disability when compared to other causes of CP. Patients should receive a complete neurological evaluation and perinatal workup. Neuroimaging findings help characterize structural brain abnormalities and predict outcome. References Alarcon A, Martinez-Biarge M, Cabañas F, Hernanz A, Quero J, Garcia-Alix

auditory evoked potentials, 223 biopsies, 245 and cerebellar dysfunction, 243 gliomas, 233 tumors, 243 C CADASIL with chronic microbleeds, 52f with encephalopathic presentation, 55f with involvement of posterior fossa, centrum semiovale, and corpus callosum, 53f with spinal involvement, 54f Cafè-au-lait, 301, 302f Canavan disease

auditory evoked potentials, 223 biopsies, 245 and cerebellar dysfunction, 243 gliomas, 233 tumors, 243 C CADASIL with chronic microbleeds, 52f with encephalopathic presentation, 55f with involvement of posterior fossa, centrum semiovale, and corpus callosum, 53f with spinal involvement, 54f Cafè-au-lait, 301, 302f Canavan disease

auditory evoked potentials, 223 biopsies, 245 and cerebellar dysfunction, 243 gliomas, 233 tumors, 243 C CADASIL with chronic microbleeds, 52f with encephalopathic presentation, 55f with involvement of posterior fossa, centrum semiovale, and corpus callosum, 53f with spinal involvement, 54f Cafè-au-lait, 301, 302f Canavan disease

auditory, memory, Wernicke's area (language comprehension) - Occipital lobe — primary visual cortex **Cerebellum** — fine motor coordination, balance **Brainstem** (midbrain, pons, medulla) — vital functions (respiration, heart rate, consciousness) **Diencephalon:** - Thalamus — sensory relay station ("gateway to the cortex") - Hypothalamus — homeostasis, pituitary gland control, drives (hunger, thirst