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Anticoagulants ### Heparins **Unfractionated heparin (UFH):** - Mechanism: activates antithrombin III → inhibits IIa and Xa - Monitoring: APTT (target 60–100 s in VTE treatment) - Reversal

anticoagulant therapy for at least 6 months.Page 139 Clinical Red Flags • Acute ataxia following blunt trauma, which can be major or minor. • Acute and severe headache, especially along the posterior head or with focal neurological deficits. • Patients with connective tissue disorders or arteriopathies. • Signs

anticoagulant therapy for at least 6 months.Page 139 Clinical Red Flags • Acute ataxia following blunt trauma, which can be major or minor. • Acute and severe headache, especially along the posterior head or with focal neurological deficits. • Patients with connective tissue disorders or arteriopathies. • Signs

anticoagulant therapy for at least 6 months.Page 139 Clinical Red Flags • Acute ataxia following blunt trauma, which can be major or minor. • Acute and severe headache, especially along the posterior head or with focal neurological deficits. • Patients with connective tissue disorders or arteriopathies. • Signs

reversible encephalopathy syndrome (PRES), and tumors. Final Diagnosis Middle cerebral artery infarct with status epilepticus. Discussion Pediatric ischemic stroke is a rare condition, especially in neonates. Patients who present with focal seizures during the early post-stroke period (first 6 hours) have the most significant

reversible encephalopathy syndrome (PRES), and tumors. Final Diagnosis Middle cerebral artery infarct with status epilepticus. Discussion Pediatric ischemic stroke is a rare condition, especially in neonates. Patients who present with focal seizures during the early post-stroke period (first 6 hours) have the most significant

reversible encephalopathy syndrome (PRES), and tumors. Final Diagnosis Middle cerebral artery infarct with status epilepticus. Discussion Pediatric ischemic stroke is a rare condition, especially in neonates. Patients who present with focal seizures during the early post-stroke period (first 6 hours) have the most significant

anticoagulant, anti-Sm, and anti-dsDNA.40 In a study looking at Sjögren syndrome, males presented with significantly higher levels of ANA, IgA, and rheumatoid factor compared with females.41 A summary of recommended screening and diagnostic laboratory tests can be found in Table 4.1. TABLE