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5 Arthroplasty in the hypermobile patient Annabelle Davey Christopher L. Antonacci Olga Solovyova Introduction Joint hypermobility is defined as excessive motion of a synovial joint.1 It is often used interchangeably with laxity or hyperlaxity, and hypermobile patients will frequently describe themselves as “double-jointed.”2 Hypermobility may be idiopathic

5), 527–537. doi:10.1521/suli.2007.37.5.527 Grov, C., Bimbi, D. S., Nanín, J. E., & Parsons, J. T. (2006). Race, ethnicity, gender, and generational factors associated with the coming-out process among gay, lesbian, and bisexual individuals. Journal of Sex Research, 43(2), 115–121. doi:10.1080/00224490609552306 GSA Network

5), 527–537. doi:10.1521/suli.2007.37.5.527 Grov, C., Bimbi, D. S., Nanín, J. E., & Parsons, J. T. (2006). Race, ethnicity, gender, and generational factors associated with the coming-out process among gay, lesbian, and bisexual individuals. Journal of Sex Research, 43(2), 115–121. doi:10.1080/00224490609552306 GSA Network

chromosomal, gonadal, or anatomic) who have been subject to a medical system that enacted societal stigmatization of DSD (Eckstrand & Sciolla, 2014). The results included the medical profession subjecting children diagnosed with DSD to “highly invasive and sometimes damaging interventions” to “ensure sex and gender normalization” (Eckstrand & Sciolla

chromosomal, gonadal, or anatomic) who have been subject to a medical system that enacted societal stigmatization of DSD (Eckstrand & Sciolla, 2014). The results included the medical profession subjecting children diagnosed with DSD to “highly invasive and sometimes damaging interventions” to “ensure sex and gender normalization” (Eckstrand & Sciolla

chromosomes and every person a gender as that person’s self-representation as male, female, or nonbinary. Arthritis is a leading cause of disability and medical healthcare expenditure in the United States. The burden of knee osteoarthritis is strikingly greater for females,2 yet our understanding of this disparity

chromosomes Best Pract Res Clin Rheumatol 5, 2008;22: 913-922. 23. Castro-Webb N, Cozier YC, Barbhaiya

chromosomal or genetic aberrations result in distinct cell lines with different pigmentations.Page 118Page 119Page 120 Clinical Red Flags • Seizures in the first year of life, particularly focal and drug-resistant. • Hypopigmented lesions following Blaschko lines. • Psychomotor retardation. Imaging Red Flags MRI is the preferred imaging modality to detect

chromosomal or genetic aberrations result in distinct cell lines with different pigmentations.Page 118Page 119Page 120 Clinical Red Flags • Seizures in the first year of life, particularly focal and drug-resistant. • Hypopigmented lesions following Blaschko lines. • Psychomotor retardation. Imaging Red Flags MRI is the preferred imaging modality to detect

chromosomal or genetic aberrations result in distinct cell lines with different pigmentations.Page 118Page 119Page 120 Clinical Red Flags • Seizures in the first year of life, particularly focal and drug-resistant. • Hypopigmented lesions following Blaschko lines. • Psychomotor retardation. Imaging Red Flags MRI is the preferred imaging modality to detect