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cerebellar atrophy with enlarged interfolial spaces (arrows). CA can be isolated or associated with other infratentorial or supratentorial findings such as hypomyelination, progressive white matter abnormalities, involvement of the basal ganglia, dentate nuclei

cerebellar atrophy with enlarged interfolial spaces (arrows). CA can be isolated or associated with other infratentorial or supratentorial findings such as hypomyelination, progressive white matter abnormalities, involvement of the basal ganglia, dentate nuclei

cerebellar atrophy with enlarged interfolial spaces (arrows). CA can be isolated or associated with other infratentorial or supratentorial findings such as hypomyelination, progressive white matter abnormalities, involvement of the basal ganglia, dentate nuclei

nuclei (arrows) with intervening white matter edema (lentiform fork sign, arrowhead). FLAIR, Fluid-attenuated inversion recovery. Any disorder associated with thrombocytopenia can produce multiple microbleeds on susceptibility images (Fig. 75.5). The scan panels are labeled A and B. Panel A presents an axial T two spin-echo scan

nuclei (arrows) with intervening white matter edema (lentiform fork sign, arrowhead). FLAIR, Fluid-attenuated inversion recovery. Any disorder associated with thrombocytopenia can produce multiple microbleeds on susceptibility images (Fig. 75.5). The scan panels are labeled A and B. Panel A presents an axial T two spin-echo scan

nuclei (arrows) with intervening white matter edema (lentiform fork sign, arrowhead). FLAIR, Fluid-attenuated inversion recovery. Any disorder associated with thrombocytopenia can produce multiple microbleeds on susceptibility images (Fig. 75.5). The scan panels are labeled A and B. Panel A presents an axial T two spin-echo scan

cerebellar and eye movement abnormalities are expected. Striatal atrophy can result from static injury, though typically coincides with other sequelae (e.g., hemosiderin deposition, leukomalacia). Imaging Differential Diagnoses Disorders that produce relatively selective and symmetrical injury to the striatum are unusual and include metabolic, mitochondrial, and neurodegenerative disorders. Glutaric acidemia type

cerebellar and eye movement abnormalities are expected. Striatal atrophy can result from static injury, though typically coincides with other sequelae (e.g., hemosiderin deposition, leukomalacia). Imaging Differential Diagnoses Disorders that produce relatively selective and symmetrical injury to the striatum are unusual and include metabolic, mitochondrial, and neurodegenerative disorders. Glutaric acidemia type

cerebellar and eye movement abnormalities are expected. Striatal atrophy can result from static injury, though typically coincides with other sequelae (e.g., hemosiderin deposition, leukomalacia). Imaging Differential Diagnoses Disorders that produce relatively selective and symmetrical injury to the striatum are unusual and include metabolic, mitochondrial, and neurodegenerative disorders. Glutaric acidemia type

nuclei and diffuse cerebral, cerebellar, and brainstem atrophy, particularly corticospinal tracts. Aceruloplasminemia shows widespread susceptibility throughout the deep gray nuclei