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Pediatric Neurology · Chapter 101
Case 78 Sickle Cell Disease, Brain, Skull, and Bones
cell anemia (HbSS) and acute chest syndrome presented to the ER with a severe headache. He had been discharged from the pediatric unit for lower extremity pain a few weeks prior. He required prior exchange transfusions and intubation, with other complications including salmonella osteomyelitis, cholestasis, and nephropathy
Pediatric Neurology · Chapter 101
Case 78 Sickle Cell Disease, Brain, Skull, and Bones
cell anemia (HbSS) and acute chest syndrome presented to the ER with a severe headache. He had been discharged from the pediatric unit for lower extremity pain a few weeks prior. He required prior exchange transfusions and intubation, with other complications including salmonella osteomyelitis, cholestasis, and nephropathy
Pediatric Neurology · Chapter 101
Case 78 Sickle Cell Disease, Brain, Skull, and Bones
cell anemia (HbSS) and acute chest syndrome presented to the ER with a severe headache. He had been discharged from the pediatric unit for lower extremity pain a few weeks prior. He required prior exchange transfusions and intubation, with other complications including salmonella osteomyelitis, cholestasis, and nephropathy
25. Osteonecrosis of the femoral head
White males.8 Approximately 10% to 11% of patients with geriatric femoral neck fractures treated with closed reduction and percutaneous pinning will experience fixation failure and ONFH, necessitating conversion THA.11 While pediatric ONFH is usually associated with Perthes disease, these patients can also experience ONFH from
8. Hormonal influences on joint health and osteoarthritis
cells positively correlated with the secretion of synovial IL-6 and IL-8 (known to be proinflammatory cytokines) but not with GRs and ARs.47 These findings indicate upregulation of inflammatory factors might increase the expression of ERRs or vice versa, whereas ARs have mainly an antiinflammatory effect
13. Infection risk
white blood cell. From McNally M, Sousa R, Wouthuyzen-Bakker M, et al. The EBJIS definition of periprosthetic joint infection. Bone Joint J. 2021;103-B(1):18-25. Pathogenesis and microbiology The development of bacterial biofilms is thought to play an essential
4. Autoimmune disorders
cell receptors.4,19 Others have examined the role of the two X chromosomes in females. Multiple theories have been discussed, including skewed X chromosome inactivation or the reactivation of inactivated X chromosome causing overexpression as causes of increased prevalence of ADs in females.20-22 Certain subgroups of females have
Pediatric Neurology · Chapter 77
Case 57 Café au Lait: Tip of the Iceberg
fat-suppressed M R I scan presents a cross-sectional view of the neck and lower head. A circle outlines a multilocular lesion in the left parotid region. An arrow points to another similar lesion in the left pterygoid fossa. The lesions appear as distinct round structures with
Pediatric Neurology · Chapter 77
Case 57 Café au Lait: Tip of the Iceberg
fat-suppressed M R I scan presents a cross-sectional view of the neck and lower head. A circle outlines a multilocular lesion in the left parotid region. An arrow points to another similar lesion in the left pterygoid fossa. The lesions appear as distinct round structures with
Pediatric Neurology · Chapter 77
Case 57 Café au Lait: Tip of the Iceberg
fat-suppressed M R I scan presents a cross-sectional view of the neck and lower head. A circle outlines a multilocular lesion in the left parotid region. An arrow points to another similar lesion in the left pterygoid fossa. The lesions appear as distinct round structures with
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