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Pediatric Neurology · Chapter 101

Case 78 Sickle Cell Disease, Brain, Skull, and Bones

cell anemia (HbSS) and acute chest syndrome presented to the ER with a severe headache. He had been discharged from the pediatric unit for lower extremity pain a few weeks prior. He required prior exchange transfusions and intubation, with other complications including salmonella osteomyelitis, cholestasis, and nephropathy
Hugo A. Arroyo· Elsevier Inc.· 9123456780105Book detail →
Pediatric Neurology · Chapter 101

Case 78 Sickle Cell Disease, Brain, Skull, and Bones

cell anemia (HbSS) and acute chest syndrome presented to the ER with a severe headache. He had been discharged from the pediatric unit for lower extremity pain a few weeks prior. He required prior exchange transfusions and intubation, with other complications including salmonella osteomyelitis, cholestasis, and nephropathy
Hugo A. Arroyo· Elsevier Inc.· 9123456798765Book detail →
Pediatric Neurology · Chapter 101

Case 78 Sickle Cell Disease, Brain, Skull, and Bones

cell anemia (HbSS) and acute chest syndrome presented to the ER with a severe headache. He had been discharged from the pediatric unit for lower extremity pain a few weeks prior. He required prior exchange transfusions and intubation, with other complications including salmonella osteomyelitis, cholestasis, and nephropathy
Hugo A. Arroyo· Elsevier Inc.· 8363524232526Book detail →

25.  Osteonecrosis of the femoral head

White males.8 Approximately 10% to 11% of patients with geriatric femoral neck fractures treated with closed reduction and percutaneous pinning will experience fixation failure and ONFH, necessitating conversion THA.11 While pediatric ONFH is usually associated with Perthes disease, these patients can also experience ONFH from
Claudette M. Lajam· Oxford· 7766778899887Book detail →

8.  Hormonal influences on joint health and osteoarthritis

cells positively correlated with the secretion of synovial IL-6 and IL-8 (known to be proinflammatory cytokines) but not with GRs and ARs.47 These findings indicate upregulation of inflammatory factors might increase the expression of ERRs or vice versa, whereas ARs have mainly an antiinflammatory effect
Claudette M. Lajam· Oxford· 7766778899887Book detail →

13.  Infection risk

white blood cell. From McNally M, Sousa R, Wouthuyzen-Bakker M, et al. The EBJIS definition of periprosthetic joint infection. Bone Joint J. 2021;103-B(1):18-25. Pathogenesis and microbiology The development of bacterial biofilms is thought to play an essential
Claudette M. Lajam· Oxford· 7766778899887Book detail →

4.  Autoimmune disorders

cell receptors.4,19 Others have examined the role of the two X chromosomes in females. Multiple theories have been discussed, including skewed X chromosome inactivation or the reactivation of inactivated X chromosome causing overexpression as causes of increased prevalence of ADs in females.20-22 Certain subgroups of females have
Claudette M. Lajam· Oxford· 7766778899887Book detail →
Pediatric Neurology · Chapter 77

Case 57 Café au Lait: Tip of the Iceberg

fat-suppressed M R I scan presents a cross-sectional view of the neck and lower head. A circle outlines a multilocular lesion in the left parotid region. An arrow points to another similar lesion in the left pterygoid fossa. The lesions appear as distinct round structures with
Hugo A. Arroyo· Elsevier Inc.· 8363524232526Book detail →
Pediatric Neurology · Chapter 77

Case 57 Café au Lait: Tip of the Iceberg

fat-suppressed M R I scan presents a cross-sectional view of the neck and lower head. A circle outlines a multilocular lesion in the left parotid region. An arrow points to another similar lesion in the left pterygoid fossa. The lesions appear as distinct round structures with
Hugo A. Arroyo· Elsevier Inc.· 9123456780105Book detail →
Pediatric Neurology · Chapter 77

Case 57 Café au Lait: Tip of the Iceberg

fat-suppressed M R I scan presents a cross-sectional view of the neck and lower head. A circle outlines a multilocular lesion in the left parotid region. An arrow points to another similar lesion in the left pterygoid fossa. The lesions appear as distinct round structures with
Hugo A. Arroyo· Elsevier Inc.· 9123456798765Book detail →
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