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chromosomal or genetic aberrations result in distinct cell lines with different pigmentations.Page 118Page 119Page 120 Clinical Red Flags • Seizures in the first year of life, particularly focal and drug-resistant. • Hypopigmented lesions following Blaschko lines. • Psychomotor retardation. Imaging Red Flags MRI is the preferred imaging modality to detect

chromosomal or genetic aberrations result in distinct cell lines with different pigmentations.Page 118Page 119Page 120 Clinical Red Flags • Seizures in the first year of life, particularly focal and drug-resistant. • Hypopigmented lesions following Blaschko lines. • Psychomotor retardation. Imaging Red Flags MRI is the preferred imaging modality to detect

chromosomal or genetic aberrations result in distinct cell lines with different pigmentations.Page 118Page 119Page 120 Clinical Red Flags • Seizures in the first year of life, particularly focal and drug-resistant. • Hypopigmented lesions following Blaschko lines. • Psychomotor retardation. Imaging Red Flags MRI is the preferred imaging modality to detect

5 minutes were 2 and 4, respectively. In the delivery room, the infant experienced significant respiratory distress prompting intubation. Neurologic examination showed hypotonia and few spontaneous movements including eye opening. EEG demonstrated continuous low-voltage patterns. Diagnostic Workup Head US on day 2 of life showed prominent extra-axial

5 minutes were 2 and 4, respectively. In the delivery room, the infant experienced significant respiratory distress prompting intubation. Neurologic examination showed hypotonia and few spontaneous movements including eye opening. EEG demonstrated continuous low-voltage patterns. Diagnostic Workup Head US on day 2 of life showed prominent extra-axial

5 minutes were 2 and 4, respectively. In the delivery room, the infant experienced significant respiratory distress prompting intubation. Neurologic examination showed hypotonia and few spontaneous movements including eye opening. EEG demonstrated continuous low-voltage patterns. Diagnostic Workup Head US on day 2 of life showed prominent extra-axial